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HIGHER EFFICACY

SODIUM SUCCINATE

Affects the main factors of OA progression:

  Hypoxia Color

 Energy Deficiency

 Acidosis

  Free-radical Lipid Peroxidation

  Structural & Functional Impairments Of The Cartilage Matrix 

SUCCINATE  is an intermediate in the Krebs Cycle, and energy-yielding process

CARTILAGE MODIFYING EFFECTS OF DIART

45 days (Animal Mode)

"With DIART, complete filling of the bony-cartilaginous defect by the regenerate in 80% cases"

Monopreparation of HA

DIART Preparation

90 days post-injury (Animal Study)

Monopreparation of HA

Partial filling of the bony-cartilaginous defect by the regenerate in administration of mono-preparation of hyaluronic acid. Loss of luster and appearance of roughness of the articular cartilage

DIART Preparation

Complete filling of the bony-cartilaginous defect by the regenerate in intra-articular administration of hyaluronic acid with sodium succinate. (DIART preparation)

DEVELOPMENT OF DEGENERATIVE CHANGES (KL GRADE 0-111)

3 - 12 Months

Results were maintained at 12 months without any Grade III

DIART Group n=44

(DIART weekly injections after absence of
all inflammation symptoms and exudate
(average 5-6 weeks)

6 Months

12 Months

Significant progression of OA in Comparison group

Comparison Group n=42

DIART Group n=44

(DIART weekly injections after absence of all inflammation symptoms and exudate
(average 5-6 weeks)

Comparison Group n=42

HOW DIART HELPS

DIART insertion directly to the seat of the pathological process helps to normalize key pathological factors* in traumatic knee injuries and also slows down the progression of OA while restoring the antioxidant defense in the affected joint.

                                                   Proven to slow down OA progression

                                                   Viscoinduction (stabilised)

 

Proven to slow down OA progression

Viscoinduction (stabilised)

DIART is a unique patented formulation that combines of Hyaluronic acid and Sodium Succinate for intra-articular administration, which have Antioxidants, Stabilizing, Chondrocytes-Stimulating and Chondroprotective properties affecting key pathogenetic mechanism in osteoarthritis development that is often left without treatment.

DIART is a unique patented formulation that combines of Hyaluronic acid and Sodium Succinate for intra-articular administration, which have Antioxidants, Stabilizing, Chondrocytes-Stimulating and Chondroprotective properties affecting key pathogenetic mechanism in osteoarthritis development that is often left without treatment.